HUPO Brain Proteomics Project workshop Dublin 2024

9:00 - 9:30 (30min)

Proteomic advancements in neurodegenerative disorders

Glending III

Peter Nilsson, KTH Royal Institute of Technology and SciLifeLab, Stockholm, Sweden
Neuroproteomics within the Human Protein Atlas

9:30 - 10:00 (30min)

Proteomic advancements in neurodegenerative disorders

Glending III

Sofia Bergström, KTH Royal Institute of Technology and SciLifeLab, Stockholm, Sweden
Protein signatures across neurodegenerative diseases

10:00 - 10:30 (30min)

Proteomic advancements in neurodegenerative disorders

Glending III

Katrin Marcus, Ruhr-Universität Bochum, Germany
Our last 20 years with neuromelanin

10:30 - 11:00 (30min)

Proteomic advancements in neurodegenerative disorders

Glending III

Maximilian Wulf, Ruhr-Universität Bochum, Germany
Neuromelanin granules as a use case for spatial proteomics

11:00 - 11:30 (30min)

Coffee break

Glending II

11:30 - 12:00 (30min)

Proteomic advancements in neurodegenerative disorders

Glending III

Darragh O'Brien, University of Oxford, UK
Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease

12:00 - 12:15 (15min)

Proteomic advancements in neurodegenerative disorders

Glending III

Dhruti Doddaballapur, Manchester University, UK
Parkinson's as a metabolism disorder

12:15 - 12:30 (15min)

Proteomic advancements in neurodegenerative disorders

Glending III

William Ryan, University of Toledo, USA
Differences between cell type specific protein kinase expression and functional activity in cerebral cortex.

12:30 - 13:30 (1h)

Lunch

VI's

13:30 - 14:30 (1h)

Proteomic applications and developments in academic-Industry collaborations

Glending III

Keynote
Christopher Whelan, Janssen Research & Development, LLC
Population-scale proteomics provides insights into diagnostics & therapeutics for human disease

14:30 - 14:45 (15min)

Proteomic applications and developments in academic-Industry collaborations

Glending III

Karin Yeoh, Preomics, Munich, Germany
Title…TBC

14:45 - 15:00 (15min)

Proteomic applications and developments in academic-Industry collaborations

Glending III

Melanie Föcking, RCSI University of Medicine and Health Sciences
Our journey to greater Sustainability, My Green Lab Accreditation

15:00 - 19:00 (4h)

Networking / free time with possibility to visit National Stud and Japanese Garden Kildare

19:00 - 22:00 (3h)

Dinner (BBQ)

Ball Room / Outdoor

	Wed. 22	Thu. 23	Fri. 24
09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 20:00 21:00 22:00 23:00	Registration & Opening reception 13:00 - 15:00 (2h) Registration & Opening reception Participants arrival, confirm registration, bookings Tea / Coffee Scones Opening of the 2024 HBPP Workshop 15:15 - 15:30 (15min) Opening of the 2024 HBPP Workshop Glending III Melanie Föcking (Chair), Sinead O’Donovan (Co-Chair) HBPP Contribution of protein deficits to the pathophysiology of psychiatric disorders 15:30 - 16:00 (30min) Contribution of protein deficits to the pathophysiology of psychiatric disorders Glending III Oliver Schubert,Adelaide,Australia Using Mendelian Randomization to Characterize Phenotype and Proteome Associations of Genetically Predicted Lithium Responsiveness Contribution of protein deficits to the pathophysiology of psychiatric disorders 16:00 - 16:30 (30min) Contribution of protein deficits to the pathophysiology of psychiatric disorders Glending III Subash Raj Susai, RCSI University of Medicine and Health Sciences Therapeutic importance of complement pathway proteins in early intervention in psychosis: A proteomic based validation study in Clinical High Risk and First Episode Psychosis patients Contribution of protein deficits to the pathophysiology of psychiatric disorders 16:30 - 17:00 (30min) Contribution of protein deficits to the pathophysiology of psychiatric disorders Glending III Rawan Alnafisah, University of Toledo, USA Dysregulated Kinase Networks in Major depressive Disorder Break 17:00 - 17:15 (15min) Break Glending II Contribution of protein deficits to the pathophysiology of psychiatric disorders 17:15 - 17:45 (30min) Contribution of protein deficits to the pathophysiology of psychiatric disorders Glending III Robert McCullumsmith, University of Toledo, USA Dark kinome…TBC Contribution of protein deficits to the pathophysiology of psychiatric disorders 17:45 - 18:00 (15min) Contribution of protein deficits to the pathophysiology of psychiatric disorders Glending III Licia Silva-Costa, University of Campinas, Brazil Identifying Molecular Patterns in Response to Antidepressants and Antipsychotics Contribution of protein deficits to the pathophysiology of psychiatric disorders 18:00 - 18:15 (15min) Contribution of protein deficits to the pathophysiology of psychiatric disorders Glending III Bradley Smith, University of Campinas, Brazil Antipsychotics Modulate the Metabolic Proteome of Adipocytes Break 18:15 - 19:00 (45min) Break Glending II Dinner 19:30 - 21:30 (2h) Dinner Linen Room Informal Networking Opportunity 21:30 - 23:55 (2h25) Informal Networking Opportunity Lawlor's The Random Inn	Proteomic advancements in neurodegenerative disorders 9:00 - 9:30 (30min) Proteomic advancements in neurodegenerative disorders Glending III Peter Nilsson, KTH Royal Institute of Technology and SciLifeLab, Stockholm, Sweden Neuroproteomics within the Human Protein Atlas Proteomic advancements in neurodegenerative disorders 9:30 - 10:00 (30min) Proteomic advancements in neurodegenerative disorders Glending III Sofia Bergström, KTH Royal Institute of Technology and SciLifeLab, Stockholm, Sweden Protein signatures across neurodegenerative diseases Proteomic advancements in neurodegenerative disorders 10:00 - 10:30 (30min) Proteomic advancements in neurodegenerative disorders Glending III Katrin Marcus, Ruhr-Universität Bochum, Germany Our last 20 years with neuromelanin Proteomic advancements in neurodegenerative disorders 10:30 - 11:00 (30min) Proteomic advancements in neurodegenerative disorders Glending III Maximilian Wulf, Ruhr-Universität Bochum, Germany Neuromelanin granules as a use case for spatial proteomics Coffee break 11:00 - 11:30 (30min) Coffee break Glending II Proteomic advancements in neurodegenerative disorders 11:30 - 12:00 (30min) Proteomic advancements in neurodegenerative disorders Glending III Darragh O'Brien, University of Oxford, UK Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease Proteomic advancements in neurodegenerative disorders 12:00 - 12:15 (15min) Proteomic advancements in neurodegenerative disorders Glending III Dhruti Doddaballapur, Manchester University, UK Parkinson's as a metabolism disorder Proteomic advancements in neurodegenerative disorders 12:15 - 12:30 (15min) Proteomic advancements in neurodegenerative disorders Glending III William Ryan, University of Toledo, USA Differences between cell type specific protein kinase expression and functional activity in cerebral cortex. Lunch 12:30 - 13:30 (1h) Lunch VI's Proteomic applications and developments in academic-Industry collaborations 13:30 - 14:30 (1h) Proteomic applications and developments in academic-Industry collaborations Glending III Keynote Christopher Whelan, Janssen Research & Development, LLC Population-scale proteomics provides insights into diagnostics & therapeutics for human disease Proteomic applications and developments in academic-Industry collaborations 14:30 - 14:45 (15min) Proteomic applications and developments in academic-Industry collaborations Glending III Karin Yeoh, Preomics, Munich, Germany Title…TBC Proteomic applications and developments in academic-Industry collaborations 14:45 - 15:00 (15min) Proteomic applications and developments in academic-Industry collaborations Glending III Melanie Föcking, RCSI University of Medicine and Health Sciences Our journey to greater Sustainability, My Green Lab Accreditation Networking / free time with possibility to visit National Stud and Japanese Garden Kildare 15:00 - 19:00 (4h) Networking / free time with possibility to visit National Stud and Japanese Garden Kildare Dinner (BBQ) 19:00 - 22:00 (3h) Dinner (BBQ) Ball Room / Outdoor	Neuroscience, biofluidomics and emerging approaches 9:00 - 9:30 (30min) Neuroscience, biofluidomics and emerging approaches Glending III Aisling Noone and Jane English, University College Cork Longitudinal multi-omics analysis of cord blood and childhood serum samples in Autism Neuroscience, biofluidomics and emerging approaches 9:30 - 10:00 (30min) Neuroscience, biofluidomics and emerging approaches Glending III Caroline May, Ruhr-Universität Bochum, Germany Investigation of inter- and intra-day variability of tear fluid regarding biomarker studies Neuroscience, biofluidomics and emerging approaches 10:00 - 10:30 (30min) Neuroscience, biofluidomics and emerging approaches Glending III Neil Taylor, Uni Tuebingen, Germany Genetic code expansion-derived approach to detect oxidative stress-induced changes in the neuronal proteome Neuroscience, biofluidomics and emerging approaches 10:30 - 11:00 (30min) Neuroscience, biofluidomics and emerging approaches Glending III Sinead O’Donovan, University of Toledo, USA Role for the ATPome in severe mental illness Coffee break 11:00 - 11:30 (30min) Coffee break Glending II Brainstorm : Future of HBPP directions 11:30 - 13:00 (1h30) Brainstorm : Future of HBPP directions Glending III All Participants discussion Closing of Workshop 13:00 - 13:15 (15min) Closing of Workshop departure